If no connection can be established from the WebClient, there are several possible causes:
Server not started
First, you should check whether the application server is running.
Service not started
The Windows service administration should be used to check whether the Password Safe Service has been started.
Port not released
Port 11016 TCP must be released on the application server.
CORS not configured
Make sure that the CORS configuration has been implemented. Further information can be found in chapter Installation WebClient